GLP-1 Inhibits High-Glucose-Induced Oxidative Injury of Vascular Endothelial Cells

Abstract The aim of this work was to evaluate the effects of glucagon-like peptide-1 (GLP-1) on high-glucose-induced oxidative stress and investigate the possible mechanisms underlying this process. We measured reactive oxygen species (ROS) production, cell apoptosis, the expression of NOX4 and its...

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Bibliographic Details
Main Authors: Quan Li, Yajun Lin, Shu Wang, Lina Zhang, Lixin Guo
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06712-z