Controlling T cells spreading, mechanics and activation by micropatterning
Abstract We designed a strategy, based on a careful examination of the activation capabilities of proteins and antibodies used as substrates for adhering T cells, coupled to protein microstamping to control at the same time the position, shape, spreading, mechanics and activation state of T cells. O...
Main Authors: | Anaïs Sadoun, Martine Biarnes-Pelicot, Laura Ghesquiere-Dierickx, Ambroise Wu, Olivier Théodoly, Laurent Limozin, Yannick Hamon, Pierre-Henri Puech |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-86133-1 |
Similar Items
-
Dependence of Spreading and Differentiation of Mesenchymal Stem Cells on Micropatterned Surface Area
by: Wei Song, et al.
Published: (2011-01-01) -
Functional Mapping of Adhesiveness on Live Cells Reveals How Guidance Phenotypes Can Emerge From Complex Spatiotemporal Integrin Regulation
by: Philippe Robert, et al.
Published: (2021-04-01) -
Dynamics of Toxoplasma gondii Oocyst Phagocytosis by Macrophages
by: Omar Ndao, et al.
Published: (2020-05-01) -
Force measurements of TCR/pMHC recognition at T cell surface.
by: Pierre-Henri Puech, et al.
Published: (2011-01-01) -
Formation and Mechanisms for Stress Induced Micropatterns of Polydimethysiloxane
by: Daniel Lin, et al.
Published: (2007)