FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells [v2; ref status: indexed, http://f1000r.es/1w7]

FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells [v2; ref status: indexed, http://f1000r.es/1w7]

The inability of targeted BRAF inhibitors to produce long-lasting improvement in the clinical outcome of melanoma highlights a need to identify additional approaches to inhibit melanoma growth. Recent studies have shown that activation of the Wnt/β-catenin pathway decreases tumor growth and cooperat...

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Bibliographic Details
Main Authors: Willliam Conrad, Michael B Major, Michele A Cleary, Marc Ferrer, Brian Roberts, Shane Marine, Namjin Chung, William T Arthur, Randall T Moon, Jason D Berndt, Andy J Chien
Format: Article
Language:English
Published: F1000 Research Ltd 2013-10-01
Series:F1000Research
Subjects:
Cell Signaling
Cellular Death & Stress Responses
Skin Cancers (incl. Melanoma & Lymphoma)
Online Access:http://f1000research.com/articles/2-134/v2

Internet

http://f1000research.com/articles/2-134/v2

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