Combination of Panax notoginseng saponins and aspirin potentiates platelet inhibition with alleviated gastric injury via modulating arachidonic acid metabolism

Combination of Panax notoginseng saponins and aspirin potentiates platelet inhibition with alleviated gastric injury via modulating arachidonic acid metabolism

High platelet reactivity and gastric mucosal injury after aspirin (ASA) treatment are associated with poor compliance and an increased risk of cardiovascular events. Panax notoginseng saponins (PNS) have been widely used for the treatment of coronary heart disease (CHD) in addition to antiplatelet d...

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Bibliographic Details
Main Authors: Wenting Wang, Lin Yang, Lei Song, Ming Guo, Changkun Li, Bin Yang, Mingming Wang, Na Kou, Jie Gao, Hua Qu, Yan Ma, Mei Xue, Dazhuo Shi
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Aspirin
Panax notoginseng saponin
Platelet inhibition
Gastric mucosal protection
Lipidomics
Arachidonic acid metabolism pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220313585

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http://www.sciencedirect.com/science/article/pii/S0753332220313585

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