Physical cues of biomaterials guide stem cell fate of differentiation: The effect of elasticity of cell culture biomaterials

It is widely accepted that stem cells directly sense the elasticity of two-dimensional (2-D) substrates and differentiate into a distinct cell type dependent on the substrate elasticity (direct-sensing differentiation: soft and hard substrates promote differentiation into soft and hard tissue lineag...

Full description

Bibliographic Details
Main Authors: Irawan Vincent, Higuchi Akon, Ikoma Toshiyuki
Format: Article
Language:English
Published: De Gruyter 2018-12-01
Series:Open Physics
Subjects:
Online Access:https://doi.org/10.1515/phys-2018-0116