Clostridial C3 Toxins Enter and Intoxicate Human Dendritic Cells
C3 protein toxins produced by <i>Clostridium (C.) botulinum</i> and <i>C. limosum</i> are mono-ADP-ribosyltransferases, which specifically modify the GTPases Rho A/B/C in the cytosol of monocytic cells, thereby inhibiting Rho-mediated signal transduction in monocytes, macroph...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
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Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/12/9/563 |