Protein complex evolution does not involve extensive network rewiring.

The formation of proteins into stable protein complexes plays a fundamental role in the operation of the cell. The study of the degree of evolutionary conservation of protein complexes between species and the evolution of protein-protein interactions has been hampered by lack of comprehensive covera...

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Bibliographic Details
Main Authors: Teunis J P van Dam, Berend Snel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18711636/pdf/?tool=EBI