Protein Carriers for Glycoconjugate Vaccines: History, Selection Criteria, Characterization and New Trends

Currently licensed glycoconjugate vaccines are composed of a carbohydrate moiety covalently linked to a protein carrier. Polysaccharides are T-cell independent antigens able to directly stimulate B cells to produce antibodies. Disease burden caused by polysaccharide-encapsulated bacteria is highest...

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Bibliographic Details
Main Authors: Francesca Micoli, Roberto Adamo, Paolo Costantino
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/6/1451