Coeloglossum viride var. bracteatum extract attenuates staurosporine induced neurotoxicity by restoring the FGF2-PI3K/Akt signaling axis and Dnmt3

Coeloglossum viride var. bracteatum extract attenuates staurosporine induced neurotoxicity by restoring the FGF2-PI3K/Akt signaling axis and Dnmt3

We previously demonstrated the antioxidant activity of Coeloglossum viride var. bracteatum extract (CE) in rat cortical neurons and in mice with chemically induced cognitive impairment. In this work, we established a staurosporine (STS)-induced toxicity model to decipher the neuroprotective mechanis...

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Bibliographic Details
Main Authors: Zhe-Ping Cai, Chang Cao, Zhe Guo, Yun Yu, Si-Jia Zhong, Rui-Yuan Pan, Haowen Liang, Rongfeng Lan, Xiao-Yan Qin
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Heliyon
Subjects:
CE
Dnmt3a
Dnmt3b
FGF2
PI3K/Akt
Staurosporine
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021016066

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http://www.sciencedirect.com/science/article/pii/S2405844021016066

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