Resveratrol as a new inhibitor of immunoproteasome prevents PTEN degradation and attenuates cardiac hypertrophy after pressure overload

Sustained cardiac hypertrophy is a major cause of heart failure (HF) and death. Recent studies have demonstrated that resveratrol (RES) exerts a protective role in hypertrophic diseases. However, the molecular mechanisms involved are not fully elucidated. In this study, cardiac hypertrophic remodeli...

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Bibliographic Details
Main Authors: Chen Chen, Lei-Xin Zou, Qiu-Yue Lin, Xiao Yan, Hai-Lian Bi, Xin Xie, Shuai Wang, Qing-Shan Wang, Yun-Long Zhang, Hui-Hua Li
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718309364