A novel understanding of postoperative complications: In vitro study of the impact of propofol on epigenetic modifications in cholinergic genes.

<h4>Background</h4>Propofol is a widely used anaesthetic drug with advantageous operating conditions and recovery profile. However, propofol could have long term effects on neuronal cells and is associated with post-operative delirium (POD). In this context, one of the contributing facto...

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Bibliographic Details
Main Authors: Caroline Holtkamp, Björn Koos, Matthias Unterberg, Tim Rahmel, Lars Bergmann, Zainab Bazzi, Maha Bazzi, Hassan Bukhari, Michael Adamzik, Katharina Rump
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217269