Allelic-Specific Regulation of xCT Expression Increases Susceptibility to Tuberculosis by Modulating microRNA-mRNA Interactions

Tuberculosis (TB) is the leading cause of death from a single infectious agent globally, and the development of multidrug resistance represents a serious health concern, particularly in the developing world. Novel effective treatments are urgently required. xCT expression is known to increase suscep...

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Bibliographic Details
Main Authors: Wenfei Wang, Yi Cai, Guofang Deng, Qianting Yang, Peijun Tang, Meiying Wu, Ziqi Yu, Fan Yang, Jianyong Chen, Oliver Werz, Xinchun Chen
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mSphere
Subjects:
xct
Online Access:https://doi.org/10.1128/mSphere.00263-20