Biosynthetic Functional Gene Analysis of Bis-Indole Metabolites from 25D7, a Clone Derived from a Deep-Sea Sediment Metagenomic Library

Biosynthetic Functional Gene Analysis of Bis-Indole Metabolites from 25D7, a Clone Derived from a Deep-Sea Sediment Metagenomic Library

This work investigated the metabolites and their biosynthetic functional hydroxylase genes of the deep-sea sediment metagenomic clone 25D7. 5-Bromoindole was added to the 25D7 clone derived Escherichia coli fermentation broth. The new-generated metabolites and their biosynthetic byproducts were loca...

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Bibliographic Details
Main Authors: Xia Yan, Xi-Xiang Tang, Dan Qin, Zhi-Wei Yi, Mei-Juan Fang, Zhen Wu, Ying-Kun Qiu
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Marine Drugs
Subjects:
deep-sea sediment
metagenomic clone
secondary metabolites
diindole derivatives
biosynthetic functional genes
cytotoxicity
Online Access:http://www.mdpi.com/1660-3397/14/6/107

Internet

http://www.mdpi.com/1660-3397/14/6/107

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