α-TEA-induced death receptor dependent apoptosis involves activation of acid sphingomyelinase and elevated ceramide-enriched cell surface membranes

<p>Abstract</p> <p>Background</p> <p>Alpha-tocopherol ether-linked acetic acid (α-TEA), an analog of vitamin E (RRR-alpha-tocopherol), is a potent and selective apoptosis-inducing agent for human cancer cells <it>in vivo </it>and <it>in vitro</it>...

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Bibliographic Details
Main Authors: Xiong Ailian, Park Sook-Kyung, Tiwary Richa, Yu Weiping, Li Jing, Sanders Bob G, Kline Kimberly
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/10/1/40