Cytokeratin-8 in Anaplastic Thyroid Carcinoma: More Than a Simple Structural Cytoskeletal Protein

Cytokeratin-8 in Anaplastic Thyroid Carcinoma: More Than a Simple Structural Cytoskeletal Protein

Anaplastic thyroid carcinoma (ATC) is almost universally fatal. Elevated keratin-8 (KRT8) protein expression is an established diagnostic cancer biomarker in several epithelial cancers (but not ATC). Several keratins, including KRT8, have been suggested to have a role in cell biology beyond that of...

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Bibliographic Details
Main Authors: Dehuang Guo, Qinqin Xu, Sarabjot Pabla, John Koomen, Paul Biddinger, Ashok Sharma, Simarjot Pabla, Rafal Pacholczyk, Chien-Chung Chang, Kevin Friedrich, Kamran Mohammed, Robert C. Smallridge, John A. Copland, Jin-Xiong She, Paul M. Weinberger
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
cytokeratin-8
anaplastic thyroid carcinoma
apoptosis
Online Access:http://www.mdpi.com/1422-0067/19/2/577

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http://www.mdpi.com/1422-0067/19/2/577

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