It All Starts at the Ends: Multifaceted Involvement of C- and N-Terminally Modified Cholinesterases in Alzheimer’s Disease

It All Starts at the Ends: Multifaceted Involvement of C- and N-Terminally Modified Cholinesterases in Alzheimer’s Disease

In Alzheimer’s disease (AD), premature demise of acetylcholine-producing neurons and the consequent decline of cholinergic transmission associate with the prominent cognitive impairments of affected individuals. However, the enzymatic activities of acetylcholinesterase (AChE) and butyrylcholinestera...

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Bibliographic Details
Main Authors: Amit Berson, Hermona Soreq
Format: Article
Language:English
Published: Rambam Health Care Campus 2010-10-01
Series:Rambam Maimonides Medical Journal
Subjects:
Acetylcholinesterase
Alzheimer’s disease
apoptosis
beta-amyloid
butyrylcholinesterase
Online Access:http://rmmj.org.il/(S(gghrnuofd030bur3cdco1rm3))/Pages/ArticleHTM.aspx?manuId=23

Internet

http://rmmj.org.il/(S(gghrnuofd030bur3cdco1rm3))/Pages/ArticleHTM.aspx?manuId=23

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