Neuroprotective Effects of Adenosine A1 Receptor Signaling on Cognitive Impairment Induced by Chronic Intermittent Hypoxia in Mice

Neuroprotective Effects of Adenosine A1 Receptor Signaling on Cognitive Impairment Induced by Chronic Intermittent Hypoxia in Mice

Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a breathing disorder associated with cognitive impairment. However, the mechanisms leading to cognitive deficits in OSAHS remain uncertain. In this study, a mouse model of chronic intermittent hypoxia (CIH) exposures were applied for simulating th...

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Bibliographic Details
Main Authors: Yichun Zhang, Hongchao Cao, Xuehao Qiu, Danfen Xu, Yifeng Chen, Gregory N. Barnes, Yunjia Tu, Adwoa Takyiwaa Gyabaah, Abdulla Husain Abdulla Ahmed Gharbal, Chenlei Peng, Jun Cai, Xiaohong Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
chronic intermittent hypoxia
cognitive dysfunction
adenosine A1 receptor
synaptic plasticity
PKC
neuroprotection
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00202/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00202/full

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