Evaluation of Effect of As2O3 on Cell Growth, Cell Cycle and Apoptosis in Human Leukemia Cell Line HL-60

Introduction: Arsenic Trioxide (As2O3) causes antitumor effects by various mechanisms, including degradation of PML-RARA in the acute promyelocytic cells, growth inhibition and induction of apoptosis. However, the precise mechanisms of these processes remain incompletely understood. The purpose of t...

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Bibliographic Details
Main Authors: Ardeshir Ghavamzade, Bahram Chahardouli, Mehrdad Nourozinia, Kamran Alimoghaddam, Saeid Abroun, Shahrbano Rostami
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2012-01-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20914.pdf&manuscript_id=20914