Comprehensive NGS Panel Validation for the Identification of Actionable Alterations in Adult Solid Tumors

Comprehensive NGS Panel Validation for the Identification of Actionable Alterations in Adult Solid Tumors

The increasing identification of driver oncogenic alterations and progress of targeted therapies addresses the need of comprehensive alternatives to standard molecular methods. The translation into clinical practice of next-generation sequencing (NGS) panels is actually challenged by the compliance...

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Bibliographic Details
Main Authors: Paula Martínez-Fernández, Patricia Pose, Raquel Dolz-Gaitón, Arantxa García, Inmaculada Trigo-Sánchez, Enrique Rodríguez-Zarco, MJose Garcia-Ruiz, Ibon Barba, Marta Izquierdo-García, Jennifer Valero-Garcia, Carlos Ruiz, Marián Lázaro, Paula Carbonell, Pablo Gargallo, Carlos Méndez, Juan José Ríos-Martín, Alberto Palmeiro-Uriach, Natalia Camarasa-Lillo, Jerónimo Forteza-Vila, Inés Calabria
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Journal of Personalized Medicine
Subjects:
next-generation sequencing (NGS)
validation
gene panels
actionable mutations
precision oncology
targeted therapies
Online Access:https://www.mdpi.com/2075-4426/11/5/360

Internet

https://www.mdpi.com/2075-4426/11/5/360

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