Identification and editing of stem-like cells in methylcholanthrene-induced sarcomas

The cancer stem cell (CSC) paradigm posits that specific cells within a tumor, so-called CSC-like cells, have differing levels of tumorigenicity and chemoresistance. Original studies of CSCs identified them in human cancers and utilized mouse xenograft models to define the cancer initiating properti...

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Bibliographic Details
Main Authors: Emilie T. E. Gross, Carlos D. Peinado, Yujin Jung, Semi Han, Beichen Liu, Endi K. Santosa, Jack D. Bui
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1404212