Expression of <it>M</it>. <it>tuberculosis</it>-induced suppressor of cytokine signaling (SOCS) 1, SOCS3, FoxP3 and secretion of IL-6 associates with differing clinical severity of tuberculosis

Expression of <it>M</it>. <it>tuberculosis</it>-induced suppressor of cytokine signaling (SOCS) 1, SOCS3, FoxP3 and secretion of IL-6 associates with differing clinical severity of tuberculosis

<p>Abstract</p> <p>Background</p> <p>Appropriate immune activation of T cells and macrophages is central for the control of <it>Mycobacterium tuberculosis</it> infections. IFN-γ stimulated responses are lowered in tuberculosis (TB), while expression of Suppr...

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Bibliographic Details
Main Authors: Masood Kiran I, Rottenberg Martin E, Salahuddin Naseem, Irfan Muhammad, Rao Nisar, Carow Berit, Islam Muniba, Hussain Rabia, Hasan Zahra
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Infectious Diseases
Subjects:
SOCS molecules
Cytokine regulation
Tuberculosis
Online Access:http://www.biomedcentral.com/1471-2334/13/13

Internet

http://www.biomedcentral.com/1471-2334/13/13

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