Novel Palladium(II) and Platinum(II) Complexes with a Fluoropiperazinyl Based Ligand Exhibiting High Cytotoxicity and Anticancer Activity In Vitro

Novel Palladium(II) and Platinum(II) Complexes with a Fluoropiperazinyl Based Ligand Exhibiting High Cytotoxicity and Anticancer Activity In Vitro

cis-Dichloro-palladium(II) and cis-dichloro-platinum(II) complexes (2, 4) of the general formula [M(N-N)Cl2] (M=Pd(II) and Pt(II), N-N= 1,2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl) benzene, (DFMPB)) and the dicationic palladium(II) complex [Pd(N-N)(CH3CN)2](BF4)2 (3) have been prepared and charac...

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Bibliographic Details
Main Authors: Kayed A. Abu-Safieh, Adnan S. Abu-Surrah, Hani D. Tabba, Huda A. AlMasri, Randa M. Bawadi, Fadila M. Boudjelal, Lubna H. Tahtamouni
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2016/7508724

Internet

http://dx.doi.org/10.1155/2016/7508724

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