Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection.

Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection.

Staphylococcus aureus produces numerous factors that facilitate survival in the human host. S. aureus coagulase (Coa) and von Willebrand factor-binding protein (vWbp) are known to clot plasma through activation of prothrombin and conversion of fibrinogen to fibrin. In addition, S. aureus clumping fa...

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Bibliographic Details
Main Authors: Natalia Malachowa, Scott D Kobayashi, Adeline R Porter, Kevin R Braughton, Dana P Scott, Donald J Gardner, Dominique M Missiakas, Olaf Schneewind, Frank R DeLeo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4918888?pdf=render

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http://europepmc.org/articles/PMC4918888?pdf=render

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