Enhanced Dissolution Efficiency of Tamoxifen Combined with Methacrylate Copolymers in Amorphous Solid Dispersions

Enhanced Dissolution Efficiency of Tamoxifen Combined with Methacrylate Copolymers in Amorphous Solid Dispersions

Amorphous solid dispersions (SDs) containing poorly soluble tamoxifen dispersed in a meth(acrylate) copolymer combination were proposed as a controlled release system. The objective of this work was to investigate the characteristics and performance of the tamoxifen–polymer mixture and evaluate the...

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Bibliographic Details
Main Authors: Dayanne T. C. da Silva, Daniela Nadvorny, Lucas J. de A. Danda, Amanda C. Q. de M. Vieira, Patricia Severino, Monica F. La R. Soares, José L. Soares-Sobrinho, Eliana B. Souto
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Crystals
Subjects:
tamoxifen
solid dispersions
supersaturation
polymer blending
recrystallization
Online Access:https://www.mdpi.com/2073-4352/10/11/1046

Internet

https://www.mdpi.com/2073-4352/10/11/1046

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