Different ways to estimate treatment effects in randomised controlled trials

Background: Regarding the analysis of RCT data there is a debate going on whether an adjustment for the baseline value of the outcome variable should be made. When an adjustment is made, there is a lot of misunderstanding regarding the way this should be done. Therefore, the aims of this educational...

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Bibliographic Details
Main Authors: Twisk J, Bosman L, Hoekstra T, Rijnhart J, Welten M, Heymans M
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865417301849