The therapeutic potential of three-dimensional multipotent mesenchymal stromal cell spheroids

The therapeutic potential of three-dimensional multipotent mesenchymal stromal cell spheroids

Abstract The efficiency of clinical trials involving transplantation of multipotent mesenchymal stromal cells (MSCs) is often insufficient due to harsh conditions present within the target tissue including hypoxia, low nutrient supply as well as inflammatory reactions. This indicates the necessity f...

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Bibliographic Details
Main Authors: Yuriy Petrenko, Eva Syková, Šárka Kubinová
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Stem Cell Research & Therapy
Subjects:
Multipotent mesenchymal stromal cells
Three-dimensional spheroids
Clinical-grade manufacturing
Paracrine activity
Survival
Therapeutic efficiency
Online Access:http://link.springer.com/article/10.1186/s13287-017-0558-6

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http://link.springer.com/article/10.1186/s13287-017-0558-6

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