Phaeophytins from Thyrsacanthus ramosissimus Moric. with inhibitory activity on human dna topoisomerase II-α

Our study reports the extraction and isolation of a new phaeophytin derivative 15¹-hydroxy-(15¹-S)-porphyrinolactone, designated anamariaine (1) herein, isolated from the chloroform fraction of aerial parts of Thyrsacanthus ramosissimus Moric. along with the known 15¹-ethoxy-(15¹-S)-porphyrinolacton...

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Main Authors: Analúcia Guedes Silveira Cabral, Fábio Henrique Tenório-Souza, Marcelo Dantas Moura, Sabrina Gondim Ribeiro Mota, Antônio Cláudio da Silva Lins, Celidarque da Silva Dias, José Maria Barbosa-Filho, Ana Maria Giulietti, Tania Maria Sarmento da Silva, Creusioni Figueredo dos Santos
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2012-01-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012001100023&lng=en&tlng=en