Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila

Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila

Contrary to dogma, evolutionarily young and dynamic genes can encode essential functions. We find that evolutionarily dynamic ZAD-ZNF genes, which encode the most abundant class of insect transcription factors, are more likely to encode essential functions in Drosophila melanogaster than ancient, co...

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Bibliographic Details
Main Authors: Bhavatharini Kasinathan, Serafin U Colmenares III, Hannah McConnell, Janet M Young, Gary H Karpen, Harmit S Malik
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
heterochromatin
positive selection
gene turnover
krab-zinc finger
gene essentiality
chromatin
Online Access:https://elifesciences.org/articles/63368

Internet

https://elifesciences.org/articles/63368

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