A Model Based Cost-Effectiveness Analysis of Routine Genotyping for CYP2D6 among Older, Depressed Inpatients Starting Nortriptyline Pharmacotherapy.

A Model Based Cost-Effectiveness Analysis of Routine Genotyping for CYP2D6 among Older, Depressed Inpatients Starting Nortriptyline Pharmacotherapy.

OBJECTIVE:Genotyping for CYP2D6 has the potential to predict differences in metabolism of nortriptyline. This information could optimize pharmacotherapy. We determined the costs and effects of routine genotyping for old aged Dutch depressed inpatients. METHODS:With a decision-tree, we modelled the f...

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Bibliographic Details
Main Authors: Elizabeth J J Berm, Judith J Gout-Zwart, Jos Luttjeboer, Bob Wilffert, Maarten J Postma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5199075?pdf=render

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http://europepmc.org/articles/PMC5199075?pdf=render

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