How drug resistance takes shape

Mutations in a hormone receptor can lead to therapeutic resistance by making it less able to bind and respond to hormone blocking drugs and by making it active, even when the hormome is not present.

Bibliographic Details
Main Authors: Rinath Jeselsohn, Myles Brown
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/14973