Rapid intrahost evolution of human cytomegalovirus is shaped by demography and positive selection.

Rapid intrahost evolution of human cytomegalovirus is shaped by demography and positive selection.

Populations of human cytomegalovirus (HCMV), a large DNA virus, are highly polymorphic in patient samples, which may allow for rapid evolution within human hosts. To understand HCMV evolution, longitudinally sampled genomic populations from the urine and plasma of 5 infants with symptomatic congenit...

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Bibliographic Details
Main Authors: Nicholas Renzette, Laura Gibson, Bornali Bhattacharjee, Donna Fisher, Mark R Schleiss, Jeffrey D Jensen, Timothy F Kowalik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3784496?pdf=render

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http://europepmc.org/articles/PMC3784496?pdf=render

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