Can PIRCHE-II Matching Outmatch Traditional HLA Matching?

Can PIRCHE-II Matching Outmatch Traditional HLA Matching?

We analyzed in a cohort of 68,606 first deceased donor kidney transplantations reported to the Collaborative Transplant Study whether an epitope-based matching of donor-recipient pairs using the Predicted Indirectly ReCognizable HLA Epitopes algorithm (PIRCHE-II) is superior to currently applied HLA...

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Bibliographic Details
Main Authors: Christian Unterrainer, Bernd Döhler, Matthias Niemann, Nils Lachmann, Caner Süsal
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
epitope matching
HLA matching
PIRCHE-II
kidney allocation
presensitization
Collaborative Transplant Study
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.631246/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.631246/full

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