A Pharmacogenetics Study in Mozambican Patients Treated with Nevirapine: Full Resequencing of TRAF3IP2 Gene Shows a Novel Association with SJS/TEN Susceptibility

A Pharmacogenetics Study in Mozambican Patients Treated with Nevirapine: Full Resequencing of TRAF3IP2 Gene Shows a Novel Association with SJS/TEN Susceptibility

Steven–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are severe adverse drug reactions, characterized by extensive epidermal detachment and erosions of mucous membrane. SJS/TEN is one of the most serious adverse reactions to Nevirapine (NVP) treatment, commonly used in developing count...

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Bibliographic Details
Main Authors: Cinzia Ciccacci, Sara Rufini, Sandro Mancinelli, Ersilia Buonomo, Emiliano Giardina, Paola Scarcella, Maria C. Marazzi, Giuseppe Novelli, Leonardo Palombi, Paola Borgiani
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
pharmacogenetics
polymorphisms
Steven–Johnson Syndrome (SJS)
Toxic Epidermal Necrolysis (TEN)
TRAF3IP2 gene
Online Access:http://www.mdpi.com/1422-0067/16/3/5830

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http://www.mdpi.com/1422-0067/16/3/5830

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