SULT2A1 gene copy number variation is associated with urinary excretion rate of steroid sulfates

SULT2A1 gene copy number variation is associated with urinary excretion rate of steroid sulfates

Human cytosolic sulfotransferases 2A1 is the main enzyme involved in the sulfate conjugation of dehydroepiandrosterone, a weak androgen and the main androgen precursor, whereas estrogens are mainly conjugated by SULT1A1. Here we have identified a copy number variation polymorphism in the SULT2A1 gen...

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Bibliographic Details
Main Authors: Jenny Jakobsson Schulze, Maria eJohansson, John-Olof eThörngren, Mats eGarle, Anders eRane, Lena eEkström
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Endocrinology
Subjects:
Androgens
Testosterone
copy number variation
SULT1A1
SULT2A1
DHEAS
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00088/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00088/full

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