Derivation and Validation of a Prognostic Model for Cancer Dependency Genes Based on CRISPR-Cas9 in Gastric Adenocarcinoma

Derivation and Validation of a Prognostic Model for Cancer Dependency Genes Based on CRISPR-Cas9 in Gastric Adenocarcinoma

As a CRISPR-Cas9-based tool to help scientists to investigate gene functions, Cancer Dependency Map genes (CDMs) include an enormous series of loss-of-function screens based on genome-scale RNAi. These genes participate in regulating survival and growth of tumor cells, which suggests their potential...

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Bibliographic Details
Main Authors: Wenjie Zhou, Junqing Li, Xiaofang Lu, Fangjie Liu, Tailai An, Xing Xiao, Zi Chong Kuo, Wenhui Wu, Yulong He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
Cancer Dependency Map
gastric adenocarcinoma
TCGA
prognostic model
invasion and metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.617289/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.617289/full

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