Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs

Approximately 40% of new chemical entities (NCEs), including anticancer drugs, have been reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic drugs (monoclonal antibodies) and small molecule drugs (nonbiologic anticancer drugs) based on effectiveness and safety p...

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Bibliographic Details
Main Authors: Phuong Tran, Yong-Chul Pyo, Dong-Hyun Kim, Sang-Eun Lee, Jin-Ki Kim, Jeong-Sook Park
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Pharmaceutics
Subjects:
Online Access:http://www.mdpi.com/1999-4923/11/3/132