Inflammatory Breast Cancer: Clinical Implications of Genomic Alterations and Mutational Profiling

Inflammatory Breast Cancer: Clinical Implications of Genomic Alterations and Mutational Profiling

Inflammatory breast cancer (IBC) is a rare and aggressive type of breast cancer whose molecular basis is poorly understood. We performed a comprehensive molecular analysis of 24 IBC biopsies naïve of treatment, using a high-resolution microarray platform and targeted next-generation sequencing (105...

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Bibliographic Details
Main Authors: Flávia L. C. Faldoni, Rolando A. R. Villacis, Luisa M. Canto, Carlos E. Fonseca-Alves, Sarah S. Cury, Simon J. Larsen, Mads M. Aagaard, Cristiano P. Souza, Cristovam Scapulatempo-Neto, Cynthia A. B. T. Osório, Jan Baumbach, Fabio A. Marchi, Silvia R. Rogatto
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
inflammatory breast cancer
microarray
gene variants
genomic scars
homologous recombination deficiency
copy number alterations
Online Access:https://www.mdpi.com/2072-6694/12/10/2816

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https://www.mdpi.com/2072-6694/12/10/2816

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