Functional evolution of a cis-regulatory module.

Lack of knowledge about how regulatory regions evolve in relation to their structure-function may limit the utility of comparative sequence analysis in deciphering cis-regulatory sequences. To address this we applied reverse genetics to carry out a functional genetic complementation analysis of a eu...

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Bibliographic Details
Main Authors: Michael Z Ludwig, Arnar Palsson, Elena Alekseeva, Casey M Bergman, Janaki Nathan, Martin Kreitman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0030093