Genome-wide characterization of the seasonal H3N2 virus in Shanghai reveals natural temperature-sensitive strains conferred by the I668V mutation in the PA subunit

Genome-wide characterization of the seasonal H3N2 virus in Shanghai reveals natural temperature-sensitive strains conferred by the I668V mutation in the PA subunit

Abstract Seasonal H3N2 influenza viruses are recognized as major epidemic viruses, exhibiting complex seasonal patterns in regions with temperate climates. To investigate the influence of viral evolution and mutations on the seasonality of influenza, we performed a genome-wide analysis of samples co...

Full description

Bibliographic Details
Main Authors: Dong Wei, De-Ming Yu, Ming-jie Wang, Dong-hua Zhang, Qi-jian Cheng, Jie-Ming Qu, Xin-xin Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Emerging Microbes and Infections
Online Access:http://link.springer.com/article/10.1038/s41426-018-0172-4

Internet

http://link.springer.com/article/10.1038/s41426-018-0172-4

Similar Items