Combined Oral and Topical Application of Pumpkin (Cucurbita pepo L.) Alleviates Contact Dermatitis Associated With Depression Through Downregulation Pro-Inflammatory Cytokines

Combined Oral and Topical Application of Pumpkin (Cucurbita pepo L.) Alleviates Contact Dermatitis Associated With Depression Through Downregulation Pro-Inflammatory Cytokines

Background: Depression and contact dermatitis (CD) are considered relatively common health problems that are linked with psychological stress. The antioxidant, anti-inflammatory, and antidepressant activities of pumpkin were previously reported.Objectives: This study aimed to evaluate the efficacy o...

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Bibliographic Details
Main Authors: Maha Jameal Balgoon, Maryam H. Al-Zahrani, Soad Al Jaouni, Nasra Ayuob
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
skin
inflammation
CD4
CD68
COX2
iNOS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.663417/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.663417/full

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