Tracking the Progression of Triple Negative Mammary Tumors over Time by Chemometric Analysis of Urinary Volatile Organic Compounds

Tracking the Progression of Triple Negative Mammary Tumors over Time by Chemometric Analysis of Urinary Volatile Organic Compounds

Previous studies have shown that volatile organic compounds (VOCs) are potential biomarkers of breast cancer. An unanswered question is how urinary VOCs change over time as tumors progress. To explore this, BALB/c mice were injected with 4T1.2 triple negative murine tumor cells in the tibia. This ty...

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Bibliographic Details
Main Authors: Mark Woollam, Luqi Wang, Paul Grocki, Shengzhi Liu, Amanda P. Siegel, Maitri Kalra, John V. Goodpaster, Hiroki Yokota, Mangilal Agarwal
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
volatile organic compounds (VOCs)
gas chromatography (GC)
mass spectrometry (MS)
headspace solid phase microextraction (HS-SPME)
breast cancer biomarkers
principal component analysis (PCA)
Online Access:https://www.mdpi.com/2072-6694/13/6/1462

Internet

https://www.mdpi.com/2072-6694/13/6/1462

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