Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins.

Respiratory syncytial virus (RSV) is a major human pathogen that infects the majority of children by two years of age. The RSV fusion (F) protein is a primary target of human antibodies, and it has several antigenic regions capable of inducing neutralizing antibodies. Antigenic site IV is preserved...

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Bibliographic Details
Main Authors: Jarrod J Mousa, Elad Binshtein, Stacey Human, Rachel H Fong, Gabriela Alvarado, Benjamin J Doranz, Martin L Moore, Melanie D Ohi, James E Crowe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006837