A Simple Criterion for Inferring CRISPR Array Direction

A Simple Criterion for Inferring CRISPR Array Direction

Inferring transcriptional direction (orientation) of the CRISPR array is essential for many applications, including systematically investigating non-canonical CRISPR/Cas functions. The standard method, CRISPRDirection (embedded within CRISPRCasFinder), fails to predict the orientation (ND prediction...

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Bibliographic Details
Main Authors: Ognjen Milicevic, Jelena Repac, Bojan Bozic, Magdalena Djordjevic, Marko Djordjevic
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
CRISPR/Cas
non-canonical functions
CRISPR array orientation
large-scale analysis
cas gene orientation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02054/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02054/full

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