Mouse Models of Influenza Infection with Circulating Strains to Test Seasonal Vaccine Efficacy

Mouse Models of Influenza Infection with Circulating Strains to Test Seasonal Vaccine Efficacy

Influenza virus infection is a significant cause of morbidity and mortality worldwide. The surface antigens of influenza virus change over time blunting both naturally acquired and vaccine induced adaptive immune protection. Viral antigenic drift is a major contributing factor to both the spread and...

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Bibliographic Details
Main Authors: Helen T. Groves, Jacqueline U. McDonald, Pinky Langat, Ekaterina Kinnear, Paul Kellam, John McCauley, Joanna Ellis, Catherine Thompson, Ruth Elderfield, Lauren Parker, Wendy Barclay, John S. Tregoning
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Influenza Vaccines
mouse models
Infection
Antibodies
Viral
vaccine drift
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00126/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00126/full

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