Double Spirocyclization of Arylidene-Δ<sup>2</sup>-Pyrrolin-4-Ones with 3-Isothiocyanato Oxindoles
Arilidene-Δ<sup>2</sup>-pyrrolin-4-ones undergo organocatalyzed double spirocyclization with 3-isothiocianato oxindoles in a domino 1,4/1,2-addition sequence. The products contain three contiguous stereocenters (<i>ee</i> up to 98%, <i>dr</i> up to 99:1, 12 exampl...
Main Authors: | Sebastijan Ričko, Žan Testen, Luka Ciber, Franc Požgan, Bogdan Štefane, Helena Brodnik, Jurij Svete, Uroš Grošelj |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | Catalysts |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4344/10/10/1211 |
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