The Synthesis and Preliminary Anticancer Evaluation of 6-Mercaptopurine -Methotrexate Conjugate as Possible Mutual Prodrug
Small molecules drug conjugate mutual prodrug design (SMDC) composed of folate &lethal agent conjugate , rigidly bonded via hydrophilic bridge& self immolative disulfide bond ; represent new interesting approaches for cancer treatment , the component of SMDC intended to be as possible...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
College of Pharmacy University of Baghdad
2019-06-01
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| Series: | Iraqi Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/851 |