The Locus Coeruleus Modulates Intravenous General Anesthesia of Zebrafish via a Cooperative Mechanism

Summary: How general anesthesia causes loss of consciousness has been a mystery for decades. It is generally thought that arousal-related brain nuclei, including the locus coeruleus (LC), are involved. Here, by monitoring locomotion behaviors and neural activities, we developed a larval zebrafish mo...

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Bibliographic Details
Main Authors: Wen-jie Du, Rong-wei Zhang, Jia Li, Bai-bing Zhang, Xiao-lan Peng, Song Cao, Jie Yuan, Cheng-dong Yuan, Tian Yu, Jiu-lin Du
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718313329