Long Non-coding RNA FER1L4 Mediates the Autophagy of Periodontal Ligament Stem Cells Under Orthodontic Compressive Force via AKT/FOXO3 Pathway

Long Non-coding RNA FER1L4 Mediates the Autophagy of Periodontal Ligament Stem Cells Under Orthodontic Compressive Force via AKT/FOXO3 Pathway

Orthodontic tooth movement is achieved by periodontal tissue remodeling triggered by mechanical force. It is essential to investigate the reaction of periodontal ligament stem cells (PDLSCs) for improving orthodontic therapeutic approaches. Autophagy is an endogenous defense mechanism to prevent mec...

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Bibliographic Details
Main Authors: Yiping Huang, Hao Liu, Runzhi Guo, Yineng Han, Yuhui Yang, Yi Zhao, Yunfei Zheng, Lingfei Jia, Weiran Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
autophagy
FER1L4
long non-coding RNA
periodontal ligament stem cells
compressive force
orthodontic tooth movement
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.631181/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.631181/full

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