Requirement of male-specific dosage compensation in Drosophila females--implications of early X chromosome gene expression.
Dosage compensation equates between the sexes the gene dose of sex chromosomes that carry substantially different gene content. In Drosophila, the single male X chromosome is hypertranscribed by approximately two-fold to effect this correction. The key genes are male lethal and appear not to be requ...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-07-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2912388?pdf=render |