Requirement of male-specific dosage compensation in Drosophila females--implications of early X chromosome gene expression.

Dosage compensation equates between the sexes the gene dose of sex chromosomes that carry substantially different gene content. In Drosophila, the single male X chromosome is hypertranscribed by approximately two-fold to effect this correction. The key genes are male lethal and appear not to be requ...

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Bibliographic Details
Main Authors: Natalie Gladstein, Meghan N McKeon, Jamila I Horabin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2912388?pdf=render