Environmental and metabolic sensors that control T cell biology

The T lymphocyte response to pathogens is shaped by the microenvironment. Environmental sensors in T cells include the nutrient sensing serine/threonine kinases AMPK (adenosine monophosphate-activated protein kinase) and mTORc1 (mammalian target of rapamycin complex 1). Other environmental sensors...

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Bibliographic Details
Main Authors: George eRamsay, Doreen eCantrell
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00099/full